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As oil prices continue to rise, fuel and chemical industries look for alternative ways to produce products. These products include fine and bulk chemicals, solvents, bio-plastics, vitamins, food additives, bio-pesticides and liquid biofuels such as bio-ethanol and bio-diesel.
Industrial biotechnology applies the tools of biology to develop innovative processes and products in a cost-efficient and eco-efficient manner, using sustainable feed stocks.

CCRES is a member-based non-profit organization with membership open to research institutions, public and private sector organizations, students, and individuals. Every day, CCRES supporters fight to make environmental education, clean energy solutions, and the green economy a reality.

The mission of CCRES ALGAE PROJECT  is to support development of innovative, sustainable, and commercially viable algae-based biotechnology solutions for energy, green chemistry, bio-products, water conservation, and CO2 abatement challenges.

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CCRES ALGAE is vital to CCRES mission and offers entrepreneurs and companies, large and small alike, a unique opportunity to actively participate in shaping the algae biotechnology research agenda for our future.Joining with commercial partners will propel research discoveries into energy and economic solutions for Croatian sustainable future.

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CROATIAN CENTER of RENEWABLE ENERGY SOURCES (CCRES)

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CCRES ALGAE TEAM

With oil prices reaching $105 a barrel for the first time since 2008, the biofuel industry is looking more attractive every day. As global demand rises and petroleum supplies diminish, countries are turning to algae for energy security.
 In smaller countries, like Croatia, where oil demand is low, and emission standards are poor, algae biofuel has the potential to significantly reduce reliance on foreign oil.
 CCRES ALGAE TEAM
works on
 
Biodiesel from MicroalgaeThe oil from the algae can be used for any combustion process. An even wider range of use for algae oil is obtained by the transesterification to biodiesel. This biodiesel can be blended with fossil diesel or can be directly driven as pure biodiesel B100.

Biodiesel from microalgae has a comparable quality as rapeseed methyl ester and meets the standard EN 14214. At biodiesel production about 12% glycerin is produced as a by-product. This glycerin is a valuable resource for the production of algae in closed ponds, the heterotrophic processes. Thus, the entire algae oil can be used as fuel.

Fish FoodAlgae provide a natural solution for the expanding fishing industry:

High-protein fish food
Replacement for existing fish meal production
Algae have nutrients of many young fishes available

The fishing industry recorded an annual growth of over 10% and, according to experts, will beat the global beef consumption in 2015.

The Technology developed by CCRES offers the opportunity to deliver part of the needed proteins for fish farming on the resulting algal biomass.

Protein for the food industryThe demand for high-quality protein for the food industry has been growing rapidly over the years.

The big growth opportunities are:

Weight control
Fitness and Sports Nutrition
Food supplements

The market volume in the protein sector is continously growing and at the rate of US $ 10.5B in 2010 and according to experts, will steadily increase to approx. $25B until 2030.

“There is intense interest in algal biofuels and bioproducts in this country and abroad, including in US,Australia, Chile, China, the European Union, Japan, Korea, New Zealand, and others,” says Branka Kalle, President of Council Croatian Center of Renewable Energy Sources (CCRES).
Advantages algae has over other sources may make it the world’s favored biofuel. Algae could potentially produce over 20 times more oil per acre than other terrestrial crops.Algae avoids many of the environmental challenges associated with conventional biofuels.Algae does not require arable land or potable water, which completely avoids competition with food resources.
 “The Asia Pacific region has been culturing algae for food and pharmaceuticals for many centuries, and these countries are eager to use this knowledge base for the production of biofuels,”says Zeljko Serdar, President of CCRES.Without sustained high prices at the pump, investment in algae will likely be driven by demand for other products. In the short term, the growth of the industry will come from governments and companies seeking to reduce their environmental impact through carbon collection.

CCRES ALGAE TEAM
part of
Croatian Center of Renewable Energy Sources (CCRES)
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BIOGORIVO TREĆE GENERACIJE

Bazeni za uzgoj algi

Proizvodnja biogoriva iz algi

Ovisnost svijeta o neobnovljivim izvorima energije, uglavnom fosilnim gorivima, trn je u oku mnogih znanstvenika i aktivista za zaštitu okoliša diljem svijeta. Samim time ne iznenađuju globalna nastojanja da se smanji ovisnost o fosilnim gorivima i pronađu ekonomski prihvatljiva alternativna goriva i da se time znatno smanje emisije štetnog ugljičnog dioksida u atmosferu. Jedna od alternativa o kojoj se najviše priča su biogoriva. Biogoriva su zbog svoje sličnosti s naftnim derivatima poprilično dobra alternativa fosilnim gorivima i korištenje biogoriva rezultira s manjim emisijama CO2 u atmosferu. Zbog toga su biogoriva ekološki puno prihvatljivija od konkurentskih fosilnih goriva. Manje ukupne emisije ugljičnog dioksida iz biogoriva rezultat su zatvorenog ugljičnog kruga – biljke i alge uzimaju iz atmosfere ugljični dioksid da bi mogle rasti, a kad se biogoriva upotrebljavaju taj isti ugljični dioksid se vraća natrag u atmosferu. Ugljični otisak fosilnih goriva ide u samo jednom smjeru – iz zemlje u atmosferu, tj.u niti jednom koraku proizvodnje i korištenja fosilnih goriva ne smanjuje se količina CO2 u atmosferi.

Alge u laboratoriju Hrvatskog Centara Obnovljivih Izvora Energije (HCOIE)
Biogorivo može biti čvrsto, tekuće ili čak plinovito gorivo koje je proizvedeno iz biološkog materijala. Kod organizama koji obavljaju fotosintezu, kao na primjer kukuruz ili soja, biljke koriste energiju sunca i vodu da bi pretvorile dostupni ugljični dioksid u ugljikohidrate, tj. da bi pohranile energiju. Ovakav proces je zapravo dvostruko koristan: ne samo da je proizvedeno gorivo, nego je za to potrošena određena količina ugljičnog dioksida pa ovakva proizvodnja goriva ima pozitivni učinak i s energetske i s ekološke točke gledanja. Iako se biogoriva mogu proizvoditi od bilo kakvih izvora ugljika, danas se uglavnom koriste razne vrste ratarskih biljaka diljem svijeta. Postoji mala razlika između različitih biljaka u smislu goriva koje se od njih proizvodi. Na primjer etanol se proizvodi od biljaka koje sadrže puno šećera (šećerna trska, kukuruz), a za proizvodnju biodizela koriste se biljke koje sadrže više ulja (soja, kanola, uljana repica).
Biogoriva imaju mnoge prednosti, ali postoje i nedostaci. Uzgajanje biljaka za proizvodnju biogoriva zahtjeva kvalitetna poljoprivredna zemljišta a to naravno povećava potražnju za takvim zemljištima i diže cijenu. Najveći problem s biogorivima je zapravo činjenica da je proizvodnja biogoriva pretvaranje hrane u gorivo, a to loše utječe i na cijenu i na dostupnost hrane diljem svijeta, a već sad postoji gotovo milijarda ljudi koji žive na rubu gladi. Prema tome pretvaranje hrane u gorivo ne izgleda kao logičan izbor za rješavanje energetskih problema.
Prednosti korištenja algi za proizvodnju biogoriva 
Proizvodnja biogoriva iz algi ima mnoge prednosti koje taj postupak čine gotovo savršenim izvorom goriva. Alge rastu 50 do 100 puta brže od tradicionalnih kultura za proizvodnju biogoriva. Dodatna velika prednost je to što su alge jednostanični organizmi koji ne zahtijevaju svježu pitku i zemljište da bi rasli, a to znatno pojednostavnjuje proizvodnju. Prema nekim stručnjacima proizvodnja goriva iz algi je najbolja alternativa fosilnim gorivima i uz dobru podršku ta bi biogoriva u budućnosti mogla u potpunosti izbaciti fosilna goriva iz upotrebe.
Gdje se mogu uzgajati alge?
 Alge se mogu uzgajati u odvojenim vodenim površinama, čak iako voda nije dovoljno kvalitetna za piće. Alge se također mogu uzgajati i u slanoj vodi. Uzgajajući alge na površinama koje nisu pogodne za proizvodnju hrane, više zemljišta i kvalitetne vode ostaje za proizvodnju hrane. Veća količina proizvedene hrane može se onda upotrijebiti za borbu protiv gladi, a ne za proizvodnju biogoriva kao do sada. Odemo li tridesetak godina unatrag, ili da smo precizniji u 1978 godinu, možemo primijetiti da je čak i američko ministarstvo za energiju (Department of Energy – DOE) pokrenulo „Aquatic Species Program“ s ciljem istraživanja moguće proizvodnje energije i biogoriva iz algi. Prema tome, proizvodnja biogoriva iz algi nije nova ideja kao što misli većina ljudi. Usprkos dobroj ideji, ovo istraživanje nije bilo produktivno, uglavnom zbog padajućih cijena sirove nafte i činjenice da je DOE bilo prisiljeno smanjivati troškove. Sve ovo rezultiralo je gašenjem programa 1996 godine.
Usprkos gašenju, istraživanja unutar tog programa dala su vrlo važne rezultate, a najvažnije od svega je zaključak da bi proizvodnja biogoriva iz algi svakako mogla dostići željene razine. U ono doba studije su pokazale i jedan veliki nedostatak: zaključeno je da postupak ne bi bio financijski opravdan sve i da se cijena sirove nafte udvostruči. Ovaj zaključak imao je solidnu potporu sve do 2006 godine u kojoj se cijena nafte gotovo utrostručila u odnosu na prošlu dekadu, a cijena nafte je i dalje rasla. Uz trenutne probleme globalnog zatopljenja i visoke cijene sirove nafte stvorile su se idealne prilike za ponovnu evaluaciju ovog izvora energije.
Tehnologije za uzgoj algi (Algal Growth System)
 
Prozvodnja biogoriva u Hrvatskom Centru Obnovljivih Izvora Energije (HCOIE)
Proizvodnja biogoriva iz algi vrlo je zanimljivo područje istraživanja mnogim znanstvenicima diljem planeta, ja jedan on vodećih centara za takova istraživanja je laboratorij za pogone i konverziju energije (The Engines and Energy Conversion Laboratory – EECL) na sveučilištu Colorado State University. Ovaj laboratorij usmjeren je prema tehnologijama koje bi omogućile industrijska rješenja za energetske i ekološke izazove. Glavni projekt laboratorija fokusiran je na proizvodnju biogoriva iz algi i trebao bi rezultirati skalabilnom i cjenovno prihvatljivom tehnologijom za proizvodnju goriva. Jedan od glavnih igrača na tom polju svakako je tvrtka Solix Biofuels, kompanija koje je usavršila nekoliko generacija sustava za uzgoj algi (Algal Growth System – AGS), tehnologije koja je sad operativna na pokaznom polju Coyote Gulch u jugozapadnom Coloradu.
Tvrtka Solix Biofuels je vodeća u proizvodnju tehnologija za kreiranje iskoristive energije iz algi. Njihova tehnologija usmjerena je na omogućavanje velike komercijalizacije goriva temeljenih na mikroalgama i dodatnih koprodukata. Alge se mogu uzgajati na dva osnovna načina – sustav otvorenog bazena (prirodnog ili umjetno napravljenog) ili umjetni zatvoreni sustav. Alge moraju biti vrlo otporne na nametnike za uzgoj u otvorenim sustavima jer su to uvjeti koje nije lako kontrolirati.
Bez kontroliranih uvjeta teško je održavati rast željene vrste algi, odnosno održati rast na optimalnoj razini za proizvodnju biogoriva. Ovo je glavni razlog zašto Solix Biofuels uglavnom razvija zatvorene sustave za uzgoj algi. Zatvoreni sustavi imaju nekoliko prednosti: ne samo da zatvoreni sustavi omogućavaju uzgoj određene kulture, nego se alge u tim sustavima mogu direktno hraniti visoko koncentriranim ugljičnim dioksidom iz industrijskih procesa, a to naravno maksimizira količinu „ulovljenog“ ugljičnog dioksida koji bi inače bio ispušten u atmosferu. Prvi prototip AGS sustava napravljen je 2006 godine. Od onda kompanija radi na usavršavanju tehnologije i znatno je proširila površinu na kojima uzgaja alge. Posljednji veliki uspjeh dolazi iz srpnja 2009 kad su instalirali veliki sustav za proizvodnju biogoriva na pokaznom polju Coyote Gulch.
Što su zapravo postigli? 
Započeli su s velikim izazovom: prvo je trebalo razviti procese za skupljanje podataka i kontroliranje rasta ta automatizirani AGS. Željeli su jedinstvenu tehnološku platformu koja bi podržavala i prirodne i industrijske operacije. U prirodnim uvjetima sustav treba biti prilagodljiv pa je bilo potrebno mnogo kemijskih i fizičkih senzora te kontrola protoka. Za operacije u industrijskom okruženju glavni je naglasak bio na stabilnoj, pouzdanoj i jednostavnoj platformi koja ima sučelja prema industrijskoj instrumentaciji i kontrolama. Industrijska okruženja također moraju imati sustave skupljanja podataka u zajednički repozitorij da bi se informacije mogle jedinstveno prezentirati svim zainteresiranim stranama: menadžerima, operativi i odjelu za istraživanja i razvoj. Zbog toga je kreiran cijeli sustav za nadzor i skupljanje podataka (Supervisory Control and Data Acquisition) uključujući i sučelje za monitoriranje i kontrolu rasta algi.
Pokusna energana uključuje raznovrsne sustave izgrađene za proizvodnju plina i tokova vode, sam sustav za uzgoj algi, sustave za skupljanje algi i konačno sustave za proizvodnju biogoriva. Svi ovi sustavi omogućuju im vrlo precizno skupljanje podataka i ispitivanje odaziva različitih vrsta algi na različite uvjete uzgoja.
Zaključak 
Alge u procesu HCOIE
Biogoriva temeljena na algama definitivno imaju potencijala pokrenuti revoluciju u energetskoj industriji i mogla bi igrati vodeću ulogu u borbi protiv stakleničkih plinova i klimatskih promjena. Naravno, da bi se došlo do toga morat će se pokrenuti još mnoga istraživanja i biti će potrebna znatna financijska sredstva. Kompanije poput Solix Biofuels su pioniri koji bi mogli pogurati ovaj energetski sektor u jedan od najkompetitivnijih na energetskom tržištu. Lobiji iza fosilnih goriva su još uvijek prejaki, ali s rastućim problemom globalnih klimatskih promjena ti lobiji bi uskoro mogli u određenoj mjeri oslabiti, čime bi se širom otvorila vrata alternativnim gorivima. Jedna od alternativa koja svakako zaslužuje pažnju u godinama koje dolaze su biogoriva iz algi. Njihov energetski potencijal, činjenica da ne pretvaramo hranu u gorivo i znatno smanjene ukupne emisije stakleničkih plinova trebali bi im osigurati dovoljna financijska sredstva za daljnja istraživanja.
Potražnja za energijom neće se smanjivati u godinama koje dolaze nego će rasti i biti će potrebna alternativna goriva bez obzira koliko će dominantna ostati fosilna goriva. Proizvodnja biogoriva iz algi mogla bi biti jedna od iznenađujućih takmaca na polju alternativnih goriva u ne tako dalekoj budućnosti, osobito ako cijene fosilnih goriva budu rasle. A u međuvremenu bi kompanije i udruženja poput američke Solix Biofuels ili hrvatskog HCOIE trebale nastaviti svoja istraživanja i ukazivati na prednosti koje ovakav proces ima. Ovime bi se svijest o toj alternativi znatno proširila i implementacija proizvodnje na globalnoj razini postala bi moguća kad za to dođe vrijeme.
Hrvatski Centar Obnovljivih Izvora Energije (HCOIE)
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Astaxanthin from Haematococcus pluvialis

Astaxanthin from Haematococcus pluvialis

 Astaxanthin
President & CEO of CCRES
 Astaxanthin
Astaxanthin, a member of the carotenoid family, it is a dark red pigment and the main carotenoid found in algae and aquatic animals. It is responsible for the red/pink coloration of crustaceans, shellfish, and the flesh of salmonoids. Algatechnologies produces astaxanthin from the microalga Haematococcus pluvialis, the richest known natural source for astaxanthin.
Astaxanthin however, is more than just a red pigment, it is primarily an extremely powerful antioxidant. It has the unique capacity to quench free radicals and reactive species of oxygen and to inhibit lipid peroxidation. Studies have shown astaxanthin to be over 500 times stronger than vitamin E and much more potent than other carotenoids such as lutein, lycopene and β-carotene.
Astaxanthin was found to have beneficial effects in many health conditions related to the Central Nervous System (CNS) disorders, skin health, joint health, muscle endurance, as well as to the cardiovascular, immune, eye and other systems.

Natural astaxanthin – molecule properties

Astaxanthin (3,3’-dihydroxy-β-β-carotene-4,4’-dione) is a xanthophyll  carotenoid,  commonly found in marine environments where it gives an orange-pink coloration to several sea-species.



CCRES  Haematococcus pluvialis
Astaxanthin has two chiral centers, at the 3 and 3′ positions. The main astaxanthin stereoisomer (3S, 3S’) found in the microalga Haematococcus pluvialis is the main form found in wild salmon.

CCRES  Haematococcus pluvialis
 Astaxanthin consists of geometric isomers (trans and cis). the cis isomers display higher bioavailability and potency in humans This isomer is abundant (up to 20%) in the natural astaxanthin complex produced by the microalga Haematococcus pluvialis.

CCRES  Haematococcus pluvialis

The astaxanthin in Haematococcus pluvialis microalgae occurs in the esterified form, which is more stable than the free astaxanthin form.

CCRES  Haematococcus pluvialis

Astaxanthin cannot be synthesized by animals and humans and must be provided in the diet. Natural astaxanthin has been part of the human diet for thousands of years.


CCRES  Haematococcus pluvialis

Astaxanthin, unlike most carotenes is not converted to vitamin A (retinol) in the human body.


CCRES  Haematococcus pluvialis

Natural astaxanthin has no “pro-oxidant” activity – It does not become an exhausted oxidant thanks to its unique molecule structure that is able to release the excess of energy as heat.

CCRES  Haematococcus pluvialis
 Astaxanthin has been shown to actually cross the blood-brain and blood-retina barriers, meaning it can positively impact disorders related to brain and the central nervous system.
 
 Astaxanthin
CCRES ALGAE PROJECT
part of
CROATIAN CENTER of RENEWABLE ENERGY SOURCES (CCRES)
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CCRES Algae Project Q&A

 

 CCRES ALGAE
CCRES Algae Project
Q&A

See answers to common questions about growing algae for biofuel production.

Algae’s potential
What makes algae a better alternative fuel feedstock than cellulosic feedstocks, such as switchgrass or miscanthus?
What transportation fuels can algae produce?
How much fuel can algae produce?
Where could this type of algae grow?
What can you do with material derived from algae production not used for fuel?

Economics
How much would a gallon of algae-based transportation fuel cost if it were available at a service station today?
What can accelerate the commercial availability of algae biofuel?

Environment
How will algae-based transportation fuels impact greenhouse gas emissions?
Is the process capable of being replicated at the local level to increase energy efficiency and promote low-energy overhead?

Security
Can algae-based fuels be used in developing countries to help them bypass fossil fuel dependence?

CCRES ALGAE
Q: What makes algae a better alternative fuel feedstock than cellulosic feedstocks, such as switchgrass or miscanthus?

A: Large-scale production of resource-intensive plants, like switchgrass or miscanthus, requires a substantial amount of fertile land, fresh water, and petroleum-based fertilizer to grow. The fuel derived is ethanol, a lower-energy fuel not compatible with the infrastructure now used to transport, refine, and deliver liquid fuels, like gasoline and diesel.

Conversely, algae can produce hydrocarbons capable of being converted directly into actual gasoline or diesel fuel, which can be transported and delivered to market using the existing refinery infrastructure.

Q: What transportation fuels can algae produce?
A: Algae produce a variety of fuel and fuel precursor molecules, including triglycerides and fatty acids that can be converted to biodiesel, as well as lipids and isoprenoids that can be directly converted to actual gasoline and traditional diesel fuel. Algae can also be used to produce hydrogen or biomass, which can then be digested into methane.

Q: How much fuel can algae produce?

A: The United States consumes 140 billion gallons per year of liquid fuel. Algae can produce 3,000 gallons of liquid fuel per acre in a year, so it would take 45 million acres of algae to provide 100% of our liquid fuel requirements.

For comparison, in 2008 the United States had 90 million acres of corn and 67 million acres of soybeans in production. So growing 45 million acres of algae, while challenging, is certainly possible.

Q: Where could this type of algae grow?

A: Algae perform best under consistent warm temperatures between 20 and 30 degrees. Climates with plenty of sunshine offer optimal conditions. Ideal Croatian locations include many of the southern and southwestern areas, such as Dalmatia,(including Dalmatian hinterland ).

CCRES ALGAE
Q: What can you do with material derived from algae production not used for fuel?

A: Production of 140 billion gallons of fuel from algae would also yield about 1 trillion pounds of protein. Since algae-produced protein is very high quality, this protein could be used to feed livestock, chicken, or fish. Presently, all livestock in this country consume about 770 billion pounds of protein per year.

Q: How much would a gallon of algae-based transportation fuel cost if it were available at a service station today?

A: Today, the cost would be relatively expensive. Additional investment in research is needed to further refine and enhance the algae strains that generate such fuels. Also, more infrastructure needs to be developed to achieve the necessary economies of scale that will come with large-scale commercial production. Once overall efficiency increases, the cost of producing a gallon of gasoline from algae will dramatically reduce.

Q: What can accelerate the commercial availability of algae biofuel?

A: As viable and potentially transformational as algae-based transportation fuels have already proven, we need a much better knowledge base on algae at the microbial level. We also need to build on this platform to develop the tools and train the next generation of scientists that will help usher in the age of accessible, affordable, and sustainable fuels made from algae. That is a central component of the Croatian Center for Algae Biofuels (CCRES Algae Project).

CCRES ALGAE
Q: How will algae-based transportation fuels impact greenhouse gas emissions?

A: Production of alternative transportation fuels from algae will help reduce the amount of CO2 in the environment. Algae provide a carbon-neutral fuel because they consume more CO2 than is ultimately released into the atmosphere when algae-based fuel burns. The amount of carbon removed from the environment will depend on the number of algae farms built and the efficiency with which algae can be modified to convert CO2 to fuel products. Eventually, algae farms will likely be located adjacent to CO2 producing facilities, like power plants, resulting in potentially significant CO2 sequestration benefits.

Q: Is the process capable of being replicated at the local level to increase energy efficiency and promote low-energy overhead?

A: Absolutely. There are huge advantages to locating algae farms near urban centers. The algae consume industrial waste and contaminants, which are usually found in higher concentrations near cities. A perfect location is near a power plant, where the algae can consume flue gas and other waste, or near a wastewater treatment plant where the algae could consume significant amounts of nitrates and phosphates from the waste stream. This could result in cleaner effluent discharge, and perhaps eventually create “new” sources of non-potable water for industrial or agricultural use.

Q: Could algae-based fuels be used in developing countries to help them bypass fossil fuel dependence?

A: Algae-based fuels (and the protein byproducts derived from their production) definitely have the potential to positively impact developing countries. The requirements for farming algae are fairly straightforward and can be done almost anywhere in the world with an adequate supply of sunshine. In Africa, for example, millions of algae acres could be farmed in its less-populated regions, resulting in a reduced dependence on foreign oil and a reliable and sustainable energy supply.

 
CCRES ALGAE PROJECT
part of
Croatian Center of Renewable Energy Sources (CCRES)
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Biodiesel Experts in EU

Growing global demand for energy to power economic development and growth demands the development of cost-effective technologies for a more sustainable energy economy for Europe (and world-wide) to ensure that European industry can compete successfully on the global stage.
Energy is a vital part of our daily lives in Europe and has been for centuries. But the days of secure, cheap energy are over. We are already facing the consequences of climate change, increasing import dependence and higher energy prices.
Consequently, the EU has been developing its climate and energy policy as an integrated approach that pursues the three key objectives of:
  • security of supply: to better coordinate the EU’s supply of and demand for energy within an international context;
  • competitiveness: to ensure the competitiveness of European economies and the availability of affordable energy;
  • sustainability: to combat climate change by promoting renewable energy sources and energy efficiency.
Click to enlarge EU primary energy requirements by fuel Source: European Energy and Transport, Trends to 2030 
Click to enlarge Import dependency of the EU (in %) Source: European Energy and Transport, Trends to 2030 
These objectives have been translated into binding targets. By 2020, the EU has committed itself to:
  • reducing its greenhouse-gas emissions by 20% (or even 30% in case an international agreement is reached that commits other countries in a similar way);
  • increasing the share of renewable energies to 20% of total EU energy consumption;
  • increasing the share of renewable energies in transport to 10%;
  • improving energy efficiency by 20%.
Achieving these goals will require major breakthroughs in the research and development of new technologies. The European Strategic Energy Technology Plan (SET-Plan) – the technology pillar of the European energy and climate policy – outlines long-term energy research priorities for the horizon of 2020 to 2050. It lays the foundations for a European policy for energy technology and establishes a framework that brings together the diverse activities in the field of energy research. For more information please visit the SET-Plan section of this website.

Biodiesel Experts in EU

NOVAOL AUSTRIA GmbH Industriegelande West 3
A-2460 Bruck/Leitha

OLEON Assenedestraat 2
9940 Ertvelde
Bioro Moervaartkaai 1
B-9042 Gent
NEOCHIM Parc Industriel, zone A
7181 Feluy
Proviron Fine Chemicals nv G.Gilliotstraat 60 – zone 2
B-2620 Hemiksem
FEDIOL 168, avenue de Tervuren
(bte 12) – 1st floor
B – 1150 – Bruxelles

Rapid Oil Industry Co. Ltd. 81A, Nikola Gabrovski st.
5000 Veliko Tarnovo

Agropodnik Dobronin 315
588 13 Polna
Preol
PREOL a.s. Lovosice,
Terezinska 47
PSC 41017

Ambrosia Oils (1976) LTD Larnaka Industrial Estate,
P.O.Box 40433, 6304 Larnaka

Daka Biodiesel Bragesvej 18
DK 4100 Ringsted

Neste Renewable Fuels Oy P.O. Box 726
00095 NESTE OIL

DIESTER INDUSTRIE 12 Avenue Georges V
75008 Paris
INEOS Enterprises France SAS Z.I. Baleycourt – BP 10095
F – 55103 VERDUN Cedex
SCA Pétrole et Dérivés 7, Allée des Mousquetaires
Parc de Tréville
91078 Bondoufle Cedex
France Ester
France Ester Route d’Alençon
61400 Saint Langis les Mortagne
Nord Ester Rue Van Cauwenberghe
Zone Industrielle de Petite-Synthe
59640 Dunkerque
Veolia / SARP Industries SARP Industries
427, route du Hazay
F-78520 Limay
Centre Ouest Céreales B.P. 10036
86131 Jaunay-clan Cedex

ADM HAMBURG AG
Nippoldstrasse. 117
D-21107 Hamburg
ADM HAMBURG AG – Werk Leer
GmbH & Co. KG
Saegemuehlenstrasse. 45
D-26789 Leer (Ostfriesland)
ADM Soya Mainz GmbH Dammweg 2
55130 Mainz
CARGILL GmbH
Ruedeckenstrasse 51 / Am Hafen
D-38239 Salzgitter-Beddingen
VERBIO Diesel Bitterfeld GmbH & Co. KG
Areal B Chemiepark Bitterfeld-Wolfen, OT Greppin, Stickstoffstrasse
D-6749 Bitterfeld-Wolfen
NATURAL ENERGY WEST GmbH
Industrie Strasse 34
41460 Neuss
PETROTEC GmbH
Fürst-von-Salm-Straße 18
46313 Borken-Burlo
BIOPETROL Industries AG Baarerstrasse 53/55,
CH-6304 Zug
EcoMotion GmbH Brunnenstr. 138
D-44536 Lünen
Mannheim Bio Fuel GmbH Inselstrasse 10
D-68169 Mannheim
Vesta Biofuels Brunsbüttel GmbH
Fahrstrasse 51
D-25541 Brunsbuttel
Rheinische Bio Ester GmbH & Co. KG Duisburger Strasse 15/19
41460 Neuss
VERBAND DEUTSCHER BIODIESELHERSTELLER e.V.
Am Weidendamm 1a
D-10117 Berlin

ELIN BIOFUELS S.A.
33 Pigon Str., 145 64 Kifissia
Athens
AGROINVEST S.A. 9th km Thessaloniki-Thermi
Thermi II Building
57001 Thessaloniki
GF Energy 56 Kifisias Av. & Delfon st.,
6th floor, 151 25 Marousi,
Athens

Öko-line Hungary Kft. Városligeti fasor 47-49
H-1071 Budapest

Green Biofuels Ireland Ltd Wexford Farmers Co-op
Blackstoops, Enniscorthy Co. Wexford

ECO FOX S.r.L. Via Senigallia 29
I=61100 Pesaro
NOVAOL ITALY Via G: Spqdolini 5
20141 Milano
ITAL BI OIL S.r.l. Ital Bi Oil S.r.l.
Via Baione 222 – 224
70043 – Monopoli (BA)
OIL. B srl OIL.B srl
Via Sabotino, 2
24121 Bergamo
OXEM Strada Provinciale Km 2,6 – 27030
Mezzana Bigli (Pv)
Mythen Via Lanzone ,31
20123 MILANO
PFP S.p.A Via Scaglia Est 134
41126 Modena
Assocostieri
Unione Produttori Biodiesel
Via di Vigna Murata 40
00143 Roma

BioVenta 66 Dzintaru
Ventspils, LV-3600

Biovalue Holding BV Westlob 6
NL-9979XG Eemshaven

Croatian Center of RES Medarska 24
10000 Zagreb

IBEROL NUTASA Av. Frei Miguel Contreiras, 54A – 3º
1700-213 Lisboa
Torrejana
Torrejana Casal da Amendoeira
Apartado 2
2354-908 Riachos
Sovena Oil Seeds Portugal R. General Ferreira Martins 6, 8º
Miraflores
1495-137 Algés
APPB

Prio Strada Stelea Spatarul
nr 12, Sector 3, Bucuresti
Expur 45 Tudor Vladimirescu Bvd. District 5
050881 Bucharest
Procera Biofuels Muncii street, No.11 Fundulea city
Calarasi County, 915200

BIONET EUROPA Poligon Agro-Reus
Adria Gual 4
43206 Reus
ACCIONA Biocombustibles, S.A Av. Ciudad de la Innovación, 5
31621 Sarriguren (Navarra)
Biocombustiblies Ctra. de Valencia Km. 202
Pol. Sepes – Parcelas 145-146
16004 Cuenca
Green Fuel Avda. San Francisco Javier, 24, Ed. Sevilla I
41018 Sevilla
Stocks del Valles
Stocks Del Valles SA Pol. Ind. El Pedregar
C/. Progres, 19-21
E-08160 Montmelo Barcelona
Bio-Oils Energy, S.L. C/ Almagro 2, 4º Dcha.
28010 Madrid
BioArag Ctra A- 1240, Km 0,900 – 22540
Altorricon (Huesca)
BioNorte S.A. Poligono de la Florida 71
33958 San Martin Del Rey Aurelio
Asturias
APPA Muntaner 269
08021 Barcelona

Ecobränsle i Karlshamn AB Västra Kajen 8B
SE-374 31 Karlshamn
Norups Biorefinery AB Box 109
289 21 Knislinge
Perstorp Prastgatan 12
SE-252 24 Helsingborg

Argent Energy 5th Floor, 9 Hatton Street
London NW8 8PL
Harvest Energy 2 Cavendish Square
London, W1G 0PU
Agri Energy Northampton Road, Blisworth
Northampton, NN7 3DR

Expert Groups 

alt Prof Thierry CHOPIN University of New Brunswick Canada
alt Dr Alan CRITCHLEY Acadian Seaplants Ltd Canada
alt Dr Amir NEORI
Dr. Ami BEN AMOTZ
Israel Oceanographic & Limnological
Research Ltd
Israel
Mr John TRAVERS
(Chief executive Ireland)
Alternative energy Resources Limited LTD
(biofuels production and supply company)
Ireland
Prof Klaus LUNING Sylt Algae Farm Germany
altalt Prof Masahiro NOTOYA Tokyo University Marine Science and
Technology International Seaweed Association
Japan
alt Dr Paolo GUALTIERI CNR- Istituto di Biofisica di Pisa Italy
alt Ms Simonetta ZARRILLI United Nations Conference on Trade and
Development (UNCTAD)
Switzerland
alt Ms Sofia SEQUEIRA Galp Portugal
alt Mr Jeff TSCHIRLEY UN Food and Agricoltural Organisation
(FAO)
Italy
alt Mr Michael. B. LAKEMAN
Mr Andrew BRAFF
Algal Biomass Organisation USA
alt Mr Frédéric MONOT Institute Français du Petrol, Biotechnology
and Biomass Chemistry
France
alt Mr. Guido DEJONGH CEN – European Committee for Standardisation
(New Standardization Opportunities)
Belgium

Experts

Prof. Spiros AGATHOS Louvain University
Belgium
Ms. Maria BARBOSA WURFood & BioBased
The Netherlands
Dr. Kateřina BIŠOVÁ Czech Institute of Microbiology
Czech Republic
Mr. Jonas DAHL Danish Technological Institute
Denmark
Dr. Maeve EDWARDS Irish Seaweed Centre
Ireland
Mr. Cameron EDWARDS VESTA Biofuels Brunsbüttel
Germany
Prof. Jose FERNANDEZ SEVILLA University of Almeria
Spain
Dr. Imogen FOUBERT K.U.Leuven University
Belgium
Dr. Gloria GAUPMANN EBIO
Belgium
Dr. Sridharan GOVINDACHARY Queen’s University
Ireland
Prof. Patricia J. HARVEY University of Greenwich
UK
Mr. Sven JACOBS Howest
Belgium
Mr. Frédéric LAEUFFER TOTAL
France
Mr. Remy MARCHAL Institut Français du Pétrole
France
Mr. Riccardo MARCHETTI Oxem S.p.a
Italy
Dr. Laura MARTINELLI Studio Martinelli
Italy
Ms. Roberta MODOLO Studio Martinelli
Italy
Mr. Benoit QUEGUINEUR Irish Seaweed Centre
Ireland
Ms. Jessica RATCLIFF Irish Seaweed Centre
Ireland
Mr. Jean-François ROUS Diester Industrie
France
Ms. Briana SAPP PANGEA
Belgium
Mr. Philippe SCHILD European Commission (DR Research)
Belgium
Mr. Johannes SKARKA Karlsruher Institute of Technology
Germany
Ms. Andrea SONNLEITNER Bioenergy 2020
Austria
Mr. Julien TAIEB FEFAC
Belgium
Prof. Laurenz THOMSEN Jacobs University Bremen
Germany
Dr. Wolfgang TRUNK European Commission (DG Health)
Belgium
Mr. Dries VANDAMME K.U.Leuven University
Belgium
Mr. Peter VAN DEN DORPEL AlgaeLink N.V.
The Netherlands
Mr. Jan VANHOUTTE BEKO
Belgium
Dr. Koen VANHOUTTE Navicula
Belgium
Mr. Ignacio VASQUEZ- L European Commission (DG Climate)
Belgium
Dr. Milada VITOVÁ Czech Institute of Microbiology
Czech Republic
Ms. Annalisa VOLSE PANGEA
Belgium
Dr. Wim VYVERMAN Ghent University
Belgium
Ms. Annika WEISS KIT
Germany
Mr. Zeljko Serdar Croatian Center of RES
Croatia

Prof. Gabriel ACIEN FERNANDEZ Almeria University
Spain
Dr. Dina BACOVSKY Bioenergy 2020+ GmbH
Austria
Dr. Natascia BIONDI University of Florence
Italy
Prof. Sammy BOUSSIBA Ben‐Gurion University
Israel
Mr. Marco BROCKEN Evodos The Netherlands
Ms. Griet CASTELEYN Ghent University Belgium
Mr. Nuno COELHO AlgaFuel Portugal
Dr. Guillermo GARCIA-B.REINA University of Las Palmas Gan Canaria Spain
Mr. Guido DE JONGH CEN Belgium
Mr. Alessandro FLAMMINI FAO Aquatic Biofuels Italy
Mr. Clayton JEFFRYES Louvain University Belgium
Dr. Bert LEMMENS VITO Belgium
Dr. Stefan LEU Ben‐Gurion University Israel
Mr. Philippe MORAND CNRS France
Mr. Josche MUTH EREC Belgium
Ms. Liliana RODOLFI Fotosintetica & Microbiologica S.r.l Italy
Dr. Robin SHIELDS Swansea University UK
Dr. Raphael SLADE Imperial College London UK
Mr. Mario R. TREDICI University of Florence Italy
Ms. Sofie VAN DEN HENDE Ghent University Belgium
Mr. Ron VAN ERCK European Commission(DG Energy) Belgium
Prof. Rene WIJFFELS Wageningen Universiteit The Netherlands
Mr. Philippe WILLEMS Orineo BVBA Belgium
Dr. Attila WOOTSCH MFKK Hungary Hungary
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CCRES – ALGAE BIOFUELS AND AQUAPONICS

 

CROATIAN CENTER of RENEWABLE ENERGY SOURCES 
(CCRES)
 
Algae, the Source of Biofuels, and Aquaponics
Algae can be used as important types of biomass materials from which the biofuels can be obtained. Algae absorb the energy from the sun in the presence of carbon dioxide and store it. A number of processes can be carried out on algae to convert it into biofuels like alcohol, biodiesel and even biogas. The biodiesel obtained from algae can be mixed with petroleum diesel and it can be used for running of trucks, cars and many types of engines that use diesel. Biodiesel can also be used as the fuel in the jets, airplanes, refineries and pipelines. The biomass obtained from algae can be used as the renewable sources of energy since it is available in abundant quantities and will be available for unlimited period of time.
One of the important advantages of algae is that it can grow in any type of water like salt, fresh, and even contaminated water. It can be grown in vast sea and river water, small rain water ponds and even commercial or domestic manmade made ponds. Algae has the potential to yield 30 times more energy than the crops grown on land, which are currently being used to produce the biofuels. This could encourage the use of algae for producing biofuels instead of the land that can be used for producing food crops. The harvesting cycle of algae is 1 to 10 days, which permits several harvests in short period of time and using the resources more effectively.

Algae and Aquaponics
As described earlier, algae can be grown in any type of water and in type of water storage system. Besides the naturally occurring seas, rivers, and ponds, it can also grow in manmade ponds. The manmade ponds can be at homes for domestic purpose or in large lands made for commercial production of algae. For the better growth of algae some nutrients may be added to water. Besides using these ponds for algae growth they can also be used for the growth of fishes and other aquatic animals.
Aquaponics is the system where one can grow the fishes and plants like algae in one integrated system. The waste given by the fishes act as important nutrients for the plants, while the cover of plants provides the natural filter for the fishes in the living areas. Aquaponics is the combination of words aquaculture and hydroponics. Aquaculture is the cultivation of fish or other water based animals, while hydroponics is the growth of plants in water. In aquaponics one can grow the water animals as well the plants at the same time. Thus the manmade small or big pond can be effectively used for growing fishes as well plants like algae.
The plants usually prefer warm-water so the water in aquaponics is also warm. The fishes grown in aquaponics are of warm-water type and not of cold-water type. The fishes grown in aquaponics can be consumed by the owner, they can be given to the friend, can be sold in the market to earn money or they can be kept as the pets. The harvesting period of fishes ranges from 7 to 9 months. When aquaponics is combined with a controlled environment greenhouse, high quality crops can be grown throughout the year and in any part of the world.
Aquaponics comprises of the water tank where the fishes are raised and fed. There is a chamber, where the uneaten foods and other particles and solids are collected. The bio-filter converts ammonia into nitrates, which act as the nutrients for the plants. There is also a portion for the growth of the plants. The lowest part of tank is a sump from where fresh water is supplied to the tank and old water is removed.
The concept of aquaponics can be extended for the growth of algae. Instead of the plants, one can grow algae, which has the harvest cycle of one to ten days. At the same time the fishes can also be grown. In the period of about nine months, while the fishes will harvest once, algae will be harvested several times. The large quantities of algae collected this way can be used as the biomass for producing the biofuels like biodiesel.
The advantages of using aquaponics for the growth of algae is that in a single place harvesting of both, the algae as well as fishes can be done. This would increase the profitability for the owner if they already have aquaculture or hydroponics. While earlier they would get only a single product from the infrastructure, they could now get two products. Since harvesting time of algae is short, it would keep the owner busy and this could become a continuous source of income for them.
The major limitations of aquaponics are the high initial costs required for housing, tank, plumbing, pumps and bedding. One should also do thorough research for the chances of success of such project. The system also has number of points of failure and requires intensive maintenance.
CCRES 
special thanks to   
Escapeartist, Inc
 CROATIAN CENTER of RENEWABLE ENERGY SOURCES 
(CCRES)
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CCRES – SOURCES OF ALTERNATIVE ENERGY

CROATIAN CENTER of RENEWABLE ENERGY SOURCES 
(CCRES)
 Sources of Alternative Energy
Alternative energy or renewable energy is important for creating clean energy future not only for the individual nations but the whole world. It offers excellent alternatives to the fossil fuels to reduce the emissions of carbon dioxide and greenhouse gases. The sources of the alternative energy are inexhaustible and one can rely on them for long-term basis Here are some important sources of alternative energy:
 
1) Solar energy:
The energy obtained from the radiations of the sun is called as solar energy. Sun is the massive source of energy releasing radiations since billions of years non-stop. The radiations emitted by sun are vital for all the plant, animal and human lives on the earth. At present solar energy is being tapped successfully for a number of applications.

Solar cooker is small box type equipment used for cooking of the food without requiring any additional fuel. There are number of variations of solar cooker with different efficiencies and different sizes. Solar water heaters are used extensively for heating water that can be used for bathing, domestic use and industrial purposes. It saves lots of electricity costs and the burning of other fuels like wood, coal, LPG etc. Another very important application of the solar energy is the photovoltaic or PV cells. The PV cells comprise of the solar panels that absorb solar energy and store them in the batteries. The energy from the batteries can be used for different domestic as well industrial applications
Besides these, there are number of other applications of solar energy like solar street lights, solar lanterns, calculators, mobiles etc. Solar energy is available abundantly in countries like India, China, US and others. It is considered to be one of the most resourceful sources of energy for future.

2) Wind energy:
The energy obtained from naturally flowing wind in the atmosphere is called as wind energy. Wind energy is available extensively in specific geographical locations without any costs. The wind in motion carries kinetic energy and it can be converted into mechanical and electrical energy. Presently wind energy is widely used for the generation of electricity.
To tap the energy from wind turbines are used. The wind turbine comprises of large blades looking like the fan. The blades are attached to the hub, which in turn is mounted on a shaft When the moving wind comes in contact with the blades it causes the rotation of the blades, which in turn causes the rotation of the shaft at low speeds. This shaft is connected to the gear box and causes slow rotation of the input gears and fast rotation of output gears and shaft. The output shaft rotates in an alternator that produces electricity. To get sufficient amount of grid power, large number of wind turbines are required at a specific location, which is called as wind farm or wind power plant.

3) Hydropower:
The power obtained from the flow of water is called as hydraulic power or hydro power or water power. The alternative energy from water can be obtained in a number of ways, the most popular being the hydroelectric power plants. In these power plants huge dams are built across the flow of the river. The water is stored in the dam at large heights and it carries potential energy. When the water flows down the potential energy is converted into kinetic energy. The flowing water comes in contacts with the large water turbines and makes them rotate in the transformer that produces electricity. Hydroelectric power plants are important source of electricity in a number of countries including US, China, India, Russia, and others.
Alternative energy obtained from the tides of the oceans is called as tidal energy. The waves in the waters of the oceans can also be utilized to produce electricity.

4) Geothermal Energy:
The heat energy obtained from the deep layers of earth is called as geothermal energy. The heat is produced continuously in the deep layers of earth, which can be utilized for various purposes like heating water, operating the heat pumps, producing electricity etc. Large amount of heat is generated in the core of earth and it gets conducted through the surrounding layers of rock. It comes to the surface of the earth in various forms like lava, hot springs etc, while other heat is stored below the surface of the earth. This heat is the geothermal energy and is available in unlimited quantity.

5) Biomass energy:
Biomass is the organic material obtained from the plants. The plants absorb energy from the sun by the process of photosynthesis so the energy is store in them. The biomass is the garbage leftover by the plants in the form of fallen leaves, broken branches, dead trees, wood chips, wasted crops etc. A number of other garbage and waste materials can be considered to be biomass. The energy obtained from the biomass is called as the biomass energy.
When the biomass is heated, the chemical energy within it is converted into heat energy, which can be used for heating water, producing steam, cooking food etc. Biomass can also be used to produce the methane gas, which can be used as the fuel. Rotten garbage and human waste can also be considered as biomass that can be used to produce methane, which is called as landfill gas or biogas. Biomass can also be converted biodiesel, which can be mixed with the traditional diesel fuel to run the vehicles.
CCRES 
special thanks to   
Escapeartist, Inc
 CROATIAN CENTER of RENEWABLE ENERGY SOURCES 
(CCRES)
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CCRES – ALTERNATIVE ENERGY

 
CROATIAN CENTER of RENEWABLE ENERGY SOURCES
 (CCRES)
Alternative Energy
 
Energy has become integral parts of our day-to-day lives. Energy is required to produce electricity for domestic and industrial applications. We need energy to drive our vehicles, to run the machines, keep our houses cool and hot, run the computers and mobiles, and for a number of other purposes.
Comparison of Traditional and Alternative Energy Sources:
Traditionally we have been using fossil fuels for production of electric power and driving our vehicles. The fuels used for the generation of electric power are fossil fuels like coal and oil, and nuclear fuels like uranium. The fuels used commonly for running the vehicles are crude oils like gasoline and diesel. Alternative energy refers to the energy that is not dependent on fossil fuels, crude oil and nuclear fuels. Alternative energy, also called as renewable energy, is obtained from various sources like radiations of the sun (solar energy), wind, water, geothermal heat and tides in the oceans. Burning of fossil fuels is one of the major causes of environmental pollution and greenhouse effect. They release lots of carbon dioxide and particulate matter. The alternative or renewable energy is considered to be the clean energy since extracting energy from its sources does not produce any pollution.
The sources of energy like fossil fuels, crude oil and nuclear fuels are also called as non-renewable sources of energy since their deposits are reducing in the nature as they are being used extensively throughout the world. Fuels like coal, natural gas and oil took millions of years to develop but once used they cannot be replaced immediately. The alternative energy on the other hand is available in abundance from various sources and they get replaced easily immediately or within short period of time.
Alternative sources of energy provide unending supply of energy. For instance the solar energy from the sun will be available for unlimited period of time till the sun keeps shining. Solar energy can be collected by the collectors and it can be used for a number of applications like cooking food, heating water, generating electricity, running the vehicles etc. Similarly, the wind will keep on blowing on the surface of the earth tills its atmosphere is in place so it can be utilized for unlimited period of time. The ability of the wind to produce motion can be utilized to run the fans of the windmill and produce electricity from them.
The tidal energy is obtained from waves of the oceans having huge quantity of water that would last forever. One of the important sources of alternative energy is hydro-power used for the generation of electricity in hydroelectric power plants. Throughout the world, the hydroelectric power plants are one of the major sources for the generation of electricity. In these plants the flow of river is blocked at certain places and water is allowed to be collected at large height in the dam. The rivers have been flowing since thousands of years and continue to exist for unlimited period of time as they are replenished by rain water from time-to-time.
Geothermal energy is obtained from the lower layers of the earth usually for producing the heating effect. Once the energy is obtained from the earth, it is replaced immediately naturally and it can be used for ending period of time interval.
Another important source of alternative energy is the biomass like waste wood, leaves of the plants, broken branches and twigs of the trees, agricultural wastes, garbage, human wastes etc. The fuels obtained from biomass are called bio-fuels. Some of the common bio-fuels are ethanol, biodiesel, and natural gas. Biodiesel is a type of alternative fuel used for running of the vehicles. It is made from renewable energy sources like plant and animal fats. Biodiesel is not a petroleum fuel, but it can be easily blended with petroleum fuel diesel in various proportions.
All the above alternative sources of energy are expected to last for long intervals of time line. While the supply of coal, oil and natural gas is expected to reduce and stop in the future, the supply of energy from sources like sun, wind, water, earth, and biomass is expected to last forever.
Consumption of alternative energy in US has been increasing over the years. In the year 2009 the consumption of alternative energy in US was 7.7 quadrillion Btu, which was 8% of all the energy used in the whole nation. Half of the alternative energy was used for producing electricity, while 10% of the total electricity produced was from alternative energy sources. Besides this alternative energy sources were also used for production of heat and steam. Alternative energy was also used for transportation, and to provide heat for homes and businesses.
Alternative energy sources reduce the pressure on fossil fuels and also help keep environment clean. The only major problem is that alternative energy is expensive compared to the fossil fuels mainly because they are located in remote places and its difficult to bring them to the main grid. Some of the sources like wind and solar are not uniform during various periods of the day and the year. However, their demand has been increasing and various technologies are being developed to utilize alternative energy sources more efficiently.
CCRES 
special thanks to   
Escapeartist, Inc
 CROATIAN CENTER of RENEWABLE ENERGY SOURCES 
(CCRES)
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Human growth hormone (HGH) from algae

 

 

Rehovot, Israel-based Rosetta Green Ltd., which specializes in crop improvement for the agriculture and alternative fuel industries using unique genes called microRNAs, has successfully completed an experiment producing human growth hormone (HGH) and validated its biological activity. Proteins produced by both treated and control algae were tested with an in vitro activity test assay by an independent third party using the conventional proliferation method. The activity test assay found that Rosetta Green’s treated algae exhibited hormonal activity.

The project is part of a joint European effort to manufacture chemicals and proteins in algae, which is implemented and funded by the European Union as part of the European Commission’s Seventh Framework Program for Research and Technology Development (FP7). More than ten European organizations are participating in this project, including companies and leading universities, which has an estimated budget of about $7 million US. The project is being managed by Professor Sammy Boussiba of the Microalgal Biotechnology Laboratory of Ben Gurion University of the Negev.
Rosetta Green focuses on using microalgae to develop and produce human proteins for therapeutics, a process that reduces the currently steep drug production costs associated with using mostly mammalian cells and bacteria.

According to Amir Avniel, Rosetta Green’s CEO, “Algae may be an effective source for the production of proteins and vaccines. Rosetta Green has vast experience working with molecular methods in algae. The company worked on the development of designated algae in order to produce the protein in cooperation with the EU. Algae can be used for multiple applications such as producing chemicals, industrial food supplements, bio fuel and food. We believe that the technology that we develop provides significant advantage to improve various traits in plants and algae. We continually seek partners to develop our products and technologies.”

Growth hormone is a peptide hormone secreted by the pituitary gland. Among its functions are the regulation of protein production and the stimulation of bone growth in children. Growth hormone is normally secreted throughout a person’s life, but the amount decreases by 14% every decade after the age of 21. A deficiency in this hormone is known to cause growth block, short stature and dwarfism.

Currently, growth hormone is produced by major multi-nationals such as Pfizer, Lilly, and Merck Serono and used as a prescription medicine to treat children with growth problems and adults with hormone deficiency as well as other symptoms characterized by growth complications. Total annual sales of human growth hormone are estimated at approximately $3 Billion US.

Growth hormone is administered today primarily through daily injections over several years. The accumulated cost can reach hundreds of thousands of dollars per child. Rosetta Green believes that manufacturing the hormone using microalgae will likely reduce today’s high cost of production, which relies upon currently available techniques.

More info at http://www.rosettagreen.com/.

CCRES special thanks to Professor Sammy Boussiba of the Microalgal Biotechnology Laboratory of Ben Gurion University of the Negev.

 

CCRES ALGAE Project 

part of

Croatian Center of Renewable Energy Sources (CCRES)

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