Tag Archives: medicine

Astaxanthin carotenoid

Astaxanthin carotenoid

photo by CCRES ALGAE Team
 Astaxanthin
 Astaxanthin is found in microalgae, yeast, salmon, trout, krill, shrimp, crayfish, crustaceans, and the feathers of some birds. It provides the red color of salmon meat and the red color of cooked shellfish.
photo by CCRES ALGAE Team
Astaxanthin, unlike several carotenes and one other known carotenoid, is not converted to vitamin A (retinol) in the human body. Like other carotenoids, astaxanthin has self-limited absorption orally and such low toxicity by mouth that no toxic syndrome is known.
 
photo by CCRES ALGAE Team
 It is an antioxidant with a slightly lower antioxidant activity in some model systems than other carotenoids. However, in living organisms the free-radical terminating effectiveness of each carotenoid is heavily modified by its lipid solubility, and thus varies with the type of system being protected.

photo by CCRES ALGAE Team
While astaxanthin is a natural nutritional component, it can also be used as a food supplement. The supplement is intended for human, animal, and aquaculture consumption. The commercial production of astaxanthin comes from both natural and synthetic sources.
CCRES ALGAE TEAM
part of
CROATIAN CENTER of RENEWABLE ENERGY SOURCES (CCRES)
Tagged , , , , , , , , , , , , , , , , , ,

Astaxanthin from Haematococcus pluvialis

Astaxanthin from Haematococcus pluvialis

 Astaxanthin
President & CEO of CCRES
 Astaxanthin
Astaxanthin, a member of the carotenoid family, it is a dark red pigment and the main carotenoid found in algae and aquatic animals. It is responsible for the red/pink coloration of crustaceans, shellfish, and the flesh of salmonoids. Algatechnologies produces astaxanthin from the microalga Haematococcus pluvialis, the richest known natural source for astaxanthin.
Astaxanthin however, is more than just a red pigment, it is primarily an extremely powerful antioxidant. It has the unique capacity to quench free radicals and reactive species of oxygen and to inhibit lipid peroxidation. Studies have shown astaxanthin to be over 500 times stronger than vitamin E and much more potent than other carotenoids such as lutein, lycopene and β-carotene.
Astaxanthin was found to have beneficial effects in many health conditions related to the Central Nervous System (CNS) disorders, skin health, joint health, muscle endurance, as well as to the cardiovascular, immune, eye and other systems.

Natural astaxanthin – molecule properties

Astaxanthin (3,3’-dihydroxy-β-β-carotene-4,4’-dione) is a xanthophyll  carotenoid,  commonly found in marine environments where it gives an orange-pink coloration to several sea-species.



CCRES  Haematococcus pluvialis
Astaxanthin has two chiral centers, at the 3 and 3′ positions. The main astaxanthin stereoisomer (3S, 3S’) found in the microalga Haematococcus pluvialis is the main form found in wild salmon.

CCRES  Haematococcus pluvialis
 Astaxanthin consists of geometric isomers (trans and cis). the cis isomers display higher bioavailability and potency in humans This isomer is abundant (up to 20%) in the natural astaxanthin complex produced by the microalga Haematococcus pluvialis.

CCRES  Haematococcus pluvialis

The astaxanthin in Haematococcus pluvialis microalgae occurs in the esterified form, which is more stable than the free astaxanthin form.

CCRES  Haematococcus pluvialis

Astaxanthin cannot be synthesized by animals and humans and must be provided in the diet. Natural astaxanthin has been part of the human diet for thousands of years.


CCRES  Haematococcus pluvialis

Astaxanthin, unlike most carotenes is not converted to vitamin A (retinol) in the human body.


CCRES  Haematococcus pluvialis

Natural astaxanthin has no “pro-oxidant” activity – It does not become an exhausted oxidant thanks to its unique molecule structure that is able to release the excess of energy as heat.

CCRES  Haematococcus pluvialis
 Astaxanthin has been shown to actually cross the blood-brain and blood-retina barriers, meaning it can positively impact disorders related to brain and the central nervous system.
 
 Astaxanthin
CCRES ALGAE PROJECT
part of
CROATIAN CENTER of RENEWABLE ENERGY SOURCES (CCRES)
Tagged , , , , , , , , , , , , , , , , , , , , , , ,